CD14 anticorps

N° du produit ABIN217653

Cet anticorps anti-CD14 est un anticorps Souris Monoclonal détectant CD14 dans FACS, WB, ELISA et Func. Adapté pour Humain, Cynomolgus, Porc, Boeuf (Vache), Mouton, Chien, Lapin, Chévre, Cat, Vison et Llama.

Aperçu rapide pour CD14 anticorps (ABIN217653)

Antigène: CD14

Reactivité: Humain, Cynomolgus, Porc, Boeuf (Vache), Mouton, Chien, Lapin, Chévre, Cat, Vison, Llama

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Functional Studies (Func)

Clone: TÜK4

Détail du produit anti-CD14 anticorps

Specificité: Recognizes the human CD14 cell surface antigen. CD14 is a 55 KDa glycoprotein that contains multiple leucine-rich repeats. It is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage but a soluble form of CD14 also exists. CD14 is strongly expressed on the surface of monocytes and macrophages but has also been shown to be expressed on the surface of non-myeloid cells. CD14 functions as a pattern recognition receptor, in innate immunity for a variety of ligands, in particular for the LPS (endotoxin) of Gram-negative bacteria. Has been shown to block SDF-induced chemotaxis of U937 cells in a dose-dependent manner.

Purification: Protein G purified

niveau d'endotoxine: Low Endotoxin

Immunogène:

Type of Immunogen: Native protein

Isotype: IgG2a

Information d'application

Indications d'application: Approved: ELISA, Flo (1:100 - 1:200), Func, WB

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS.

Conseil sur la manipulation: Store undiluted.

Stock: -20 °C

Stockage commentaire: -20°C. Store undiluted.

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: Name/Gene ID: CD14

Synonyms: CD14, CD14 Molecule, CD14 antigen

ID gène: 929

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades